Electric car batteries inspire safer, cheaper way to make compounds used in...
Recent advances in battery technology, from the engineering of their cases to the electrochemistry that takes place inside them, has enabled the rapid rise of Teslas, Leafs, Volts and other electric cars.
View ArticlePromising compound selectively kills brain cancer stem cells
Scripps Research scientists have discovered a compound that potently and selectively kills the stem-like cells that make glioblastoma brain cancers so deadly.
View ArticleScientists discover a potential strategy to treat influenza A
A team of researchers from Scripps Research and Janssen Research & Development LLC has discovered an orally active small molecule that neutralizes influenza A group 1 viruses, the most common flu...
View ArticleScientists hunt down the brain circuit responsible for alcohol cravings
Scientists at Scripps Research have found that they can reverse the desire to drink in alcohol-dependent rats—with the flip of a switch. The researchers were able to use lasers to temporarily...
View ArticleDiscovery of life-extension pathway in worms demonstrates new way to study aging
An enzyme-blocking molecule can extend the lifespan of Caenorhabditis elegans roundworms by as much as 45 percent, largely by modulating a cannabinoid biological pathway, according to a study from...
View ArticleNew therapy targets cause of adult-onset muscular dystrophy
People diagnosed with myotonic dystrophy type 1 have difficulty unclenching muscles due to a genetic defect that generates toxic material within their cells. There is currently no treatment. In a new...
View ArticleBuilding blocks of DNA and RNA could have appeared together before life began...
Scientists for the first time have found strong evidence that RNA and DNA could have arisen from the same set of precursor molecules even before life evolved on Earth about four billion years ago.
View ArticleMolecules that curb errant proteins of AL amyloidosis point to new type of...
Scientists at Scripps Research have identified a group of small molecules that prevent structural changes to proteins that are at the root of AL amyloidosis, a progressive and often fatal disease.
View ArticleGene repair improves memory and seizures in adult autism model
A new study challenges the presumption that people born with developmental brain disorders such as severe autism will benefit from medical interventions only if treated during a narrow window in...
View ArticleNanotubes enable travel of Huntington's protein
A toxic protein linked to Huntington's disease can move from neuron to neuron through a nanotube tunnel whose construction is initiated by a protein called Rhes, say scientists at Scripps Research.
View ArticleUnexplored neural circuit modulates memory strength
Learning to avoid negative experiences requires an interplay of two distinct brain circuits, one to interpret "Yikes!" and drive learning, and the other, unexpectedly, to dial in the strength of that...
View ArticleMonkey-infecting virus may provide part of future HIV vaccine
A protein from Simian Immunodeficiency Virus (SIV), which can infect monkeys and apes, has shown promise as a potential component of a vaccine against Human Immunodeficiency Virus (HIV), in a new study...
View ArticleBacteria's protein quality control agent offers insight into origins of life
May 30—Our cells' process for transforming genes into useful proteins works much like an automobile factory's assembly line; there are schematics, parts, workers, motors, quality control systems and...
View ArticlePrescription drug costs steadily soar, yet price transparency is lacking
After reviewing tens of millions of insurance claims for the country's 49 most popular brand-name prescription drugs, a team from Scripps Research Translational Institute found that net prices rose by...
View ArticleOvercoming PTSD: Study reveals memory disruption drug target
Fight or flight, panic, trembling: Our brains are wired to ensure we respond instantly to fear. While that fear response may save our lives in the dangerous moment, at times people stay on high alert...
View ArticleExosomes may hold the answer to treating, diagnosing developmental brain...
Like overpacked suitcases unloaded from the underbelly of a jet, molecular satchels called exosomes are continuously deployed from all cells in the body—each one brimming with an assortment of contents...
View ArticleA chemical clue to how life started on Earth
Earth didn't always harbor life. But around 4 billion years ago, something in the environment changed, and systems with biological properties began to emerge. Many scientists believe a lively dance of...
View ArticleUS and China should collaborate, not compete, to bring AI to healthcare
In the wake of the U.S. government ordering the Chinese artificial intelligence company iCarbonX to divest its majority ownership stake in the Cambridge, Mass.-based company PatientsLikeMe, Eric Topol,...
View ArticleProtein-transport discovery may help define new strategies for treating eye...
Many forms of vision loss stem from a common source: impaired communication between the eye and the brain. And at the root of all eye-to-brain communication are the hundreds of proteins generated by...
View ArticleDiscovery of 'hidden' outbreak hints that Zika virus can spread silently
Just when international fears of contracting Zika began to fade in 2017, an undetected outbreak was peaking in Cuba—a mere 300 miles off the coast of Miami. A team of scientists at Scripps Research,...
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